June 2016

Thrombotic microangiopathy with Atypical Posterior Reversible Encephalopathy Syndrome (PRES) after kidney transplantation. A case report.

Neurological manifestation of thrombotic microangiopathy (TMA) after renal transplantation is rare and difficult to be distinguished from other conditions. A 51-year-old female with ESRD of unknown etiology received deceased donor kidney transplantation from a 57-year-old donor....Continue reading →

Gap Analysis Study before Implementation of Thailand’s National Guidelines for Point of Care Testing at Chiang Rai Province

The Bureau of Laboratory Quality Standards has published Thailand’s National Guidelines for Point-of-Care Testing (POCT) since August 2015. Still yet, the implementation of the guidelines is a great challenge....Continue reading →

Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow

Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of pathologic processes. Objective: This study is to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals...Continue reading →

The Akt/mTOR pathway is activated in verrucous carcinoma of the oral cavity

The Akt/mTOR pathway is activated in many malignancies including oral squamous cell carcinoma (OSCC). Oral verrucous carcinoma (OVC) is a low grade variant of OSCC. However, the role of the Akt/mTOR pathway in OVC remains unknown. ...Continue reading →

Anaplastic lymphoma kinase (ALK) translocation in paediatric malignant peritoneal mesothelioma: a case report of novel ALK-related tumour spectrum

To report a case of paediatric malignant peritoneal mesothelioma (MPM) with evidence of anaplastic lymphoma kinase (ALK) translocation....Continue reading →

Endometriosis with gut obstruction: a case report of 38 years old woman with acute abdominal pain

A woman, age thirty-eight years old, came to the hospital with acute diarrhea and complained of having severe abdominal pain for two days. She had no underling disease and no history of alcohol or tobacco usage. She previously had surgery for a fracture of the right femur....Continue reading →

Author : Garan Phrommee , M.D. ,

Primary renal neuroendocrine tumor: A case report and literature review

Primary renal neuroendocrine tumor or primary renal carcinoid tumor is a very rare primary tumor of the kidney. This tumor appears to be associated with horseshoe kidney and the most common clinical features being abdominal pain or hematuria. Here, we report on the case of 63-yearold Thai female who presented...Continue reading →

Difficult case in the diagnosis of pineal tumor with ectomesenchymal differentiation: teratoma versus pineal anlage tumor.

Pineal region tumors are rare and heterogeneous including germ cell tumors, pineal parenchymal tumors and neuroepithelial tumors. Amongthe pineal region tumors, germ cell tumorssuch as germinoma and teratoma are the most common, followed by pineal parenchymal tumors. We have discusseda case of 20-year-old woman...Continue reading →

Astudy of prostatic cancer in radical prostatectomyspecimenand acorrelationwithpre-operativeserum PSA levelin Chiang Mai University Hospital

To assess arelationship between serum prostate specifi c antigen (PSA) levels and pathologic parameters in radical prostatectomy (RP) specimens for prostate cancer in Chiang Mai University Hospital, Chiang Mai, Thailand....Continue reading →

Placental villous hypermaturation in idiopathic spontaneous preterm births in Srinagarind Hospital

To determine the association between preterm births (PTBs) and placental villous hypermaturation (PVH), a pathological fi nding which suggests placental insuffi ciency....Continue reading →

Automated counting of Ki-67 labeling index compares with eyeballing estimation to predict behavior of pituitary adenoma.

Pituitary adenoma has been classified as benign according to slow-growing tumor. However, some atypical pituitary adenoma may have clinical aggressiveness such as parasellar invasion and high recurrence rate.Many studies have failed to demonstrate a correlation between Ki-67 labeling index and behavior of this tumor....Continue reading →

Specificity of cytologic features of metastatic lung adenocarcinoma in malignant pleural effusion

Metastatic lung adenocarcinoma is commonly presented with effusions. The cytologic examination of the fl uid is one of the fi rst diagnostic techniques attempted in these patients. Identifi cation of the cancer cells in pleural fl uid specimens, using minimal, less invasive and cost effective intervention is crucial especially...Continue reading →

Accuracy in distinguishing between primary adenocarcinoma of cervix and adenocarcinoma of endometrium from curettage specimen by immunohistochemistry

Endometrial and endocervical adenocarcinomas can seem histologically identical and it can be diffi cult to determine the primary site of origin based on morphology alone. As the distinction is signifi cant and cannot always be made on the basis of clinical fi ndings, various immunohistochemical panels have been proposed to aid in determining...Continue reading →

Prevalence of Microsatellite instability (MSI) determined by immunohistochemical staining of MSH6 and PMS2 in patients with colorectal adenocarcinoma

Microsatellite instability(MSI) is one of the genetic abnormalities that leads to colon cancer. The defect, known as mismatch repair genes(MMR) can be either sporadic or a germ line mutation. A immunohistochemical study is one of the methods to detect MMR defects. Lots of different treatment modalities and prognosis are needed to distinguish cancer...Continue reading →

Inflammatory bowel disease: Review of histologic features

Inflammatory bowel disease (IBD) is a chronic infl ammation of the digestive tract with ulcerative colitis (UC) and Crohn’s disease (CD) being among the two most common IBD conditions. To evaluate the effi cacy of diagnosis by histomorphology, the histologic features of ninety Thai patients with IBD were evaluated...Continue reading →

Impact of the 2011 IASLC/ATS/ERS International Multidisciplinary Classifi cation on small biopsies of primary lung cancer: experience in King Chulalongkorn Memorial Hospital from 2012-2014

The 2011 international association for the study of lung cancer/ American thoracic society/ European respiratory society (IASLC/ATS/ERS ) classifi cation changed the approach for defi nite histologic diagnosis of lung cancer. The objective of this article is to describe the impact of the 2011 IASLC/ATS/ERS classifi cation on small biopsy...Continue reading →

Pulmonary neuroendocrine hyperplasia in hemoglobin Bart-induced hydrops fetalis. A model for chronic intrauterine hypoxia

The pulmonary neuroendocrine system consists of pulmonary neuroendocrine cells (PNECs) and neuroendocrine bodies (NEBs) distributed throughout the respiratory epithelium which regulate lung growth and maturation in the antenatal period. Abnormalities in this system have been linked to many hypoxia-associated pediatric pulmonary disorders....Continue reading →

Comparison of embalming techniques between formaldehyde and salt solution in human liver and brain

Formaldehyde exposure is a risk factor for cancer in humans. Recent studies have revealed that salt solution can preserve human and animal tissues with a quality equal to formaldehyde. This study is the fi rst attempt to compare effectiveness between formaldehyde and salt solution preservation by quantitative measurement of tissue discoloration, ...Continue reading →

Agreement between Rapid On-site Evaluation and Final Cytologic Diagnosis of Salivary Gland Specimens

To evaluate diagnostic agreement and compare the performance (accuracy) between rapid onsite evaluation (ROSE) and the fi nal cytologic diagnosis of salivary gland specimens....Continue reading →

Discrepancies between clinical and autopsy diagnosis in traumatic death cases in Siriraj Hospital

Hospital autopsy has been questioned regarding its utility, effectiveness, and validity. However, some discrepancies between clinical and autopsy diagnosis has been shown in previous study.While forensic autopsy, which is mostly done in traumatic death, has not been evaluated for its usefulness, the authors would like to determine...Continue reading →

P-cadherin and CD10 expression to distinguish between ductal carcinoma in situ and invasive ductal carcinoma of the breast

To utilize immunohistochemistry techniques using P-cadherin and CD10 antibodies for evaluating the expression in DCIS and IDC for distinguishing between these entities...Continue reading →

Evaluation of Adequacy and Diagnostic Histopathology Results of Endometrial Specimens Obtained by Endometrial Aspiration Procedure in Srinagarind Hospital, Khon Kaen University.

The purpose of this investigation is to evaluate the adequacy of endometrial specimens obtained by endometrial aspiration procedures using Pipelle® Endometrial Suction Currette, to determine the minimum microscopic area of endometrial fragments adequate for diagnosis, and to make a correlation between the initial diagnoses of the...Continue reading →

Molecular diagnosis of synovial sarcoma: A comparative study with histologic correlation in Ramathibodi Hospital

Synovial sarcoma (SS) is a relatively common sarcoma of soft tissue arising on extremities of young adult, which is often diagnosed by histology and immunohistochemistry. Synovial sarcoma can have various locations and may cause diagnostic dilemma in tumors arising on unusual locations. In this study, we evaluate the application of molecular test...Continue reading →

Clinicopathological Correlation of Glomerular Mesangial C4d Staining and renal outcome in IgA Nephropathy: A retrospective Cohort Study in Ramathibodi Hospital

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, particularly in Asia. Clinical manifestations vary from asymptomatic to end stage renal disease (ESRD). Currently, several studies have introduced new markers to predict prognosis including C4d which is correlated with poor clinical course....Continue reading →

Evaluation of thyroid fine needle aspiration cytology by the Bethesda reporting system: a retrospective analysis of rates and outcomes from the King Chulalongkorn Memorial Hospital

Fine-needle aspiration (FNA) cytology is a gold standard for preoperative evaluation of thyroid nodules. Recently introduced, the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has attempted to standardize reporting and cytological criteria in aspiration smears. This reporting format suggested six diagnostic categories, briefl y defi ned as follows...Continue reading →

Clinicopathological Features of Primary Thyroid Lymphomas in Thailand

Primary non-Hodgkin lymphoma (NHL) of the thyroid is a rare tumor. Some studies show association between thyroid lymphomas and concomitant thyroid diseases, mainly lymphocytic thyroiditis. However, this tumor has not been studied in Thailand. .Therefore, herein, we reviewed clinicopathological features of primary thyroid lymphoma including associated thyroid lesions....Continue reading →

Fine Needle Aspiration and Core Needle Biopsy for Diagnosis of Mediastinal Mass in Thailand

To evaluate diagnostic accuracy of fi ne needle aspiration (FNA) and core needle biopsy (CNB) in mediastinal lesions. Material and Methods: From October 2006 to September 2015, there were 45 cases of FNA and 87 cases of CNB included in this retrospective study. Results of FNA and CNB were compared with subsequent resection specimen...Continue reading →

Hepatic injury in patients with colorectal liver metastasis in Thailand

The treatment of colorectal liver metastasis is surgical resection. The chemotherapy can convert unresectable lesions to resectable lesions. However chemotherapy also causes liver injuries in remaining liver parenchyma, such as steatosis, steatohepatitis and sinusoidal dilation. These lesions cannot be distinguished from other causes,...Continue reading →

Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow

Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of primary marrow diseases. This study is designed to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals after taken out from the body (delayed fi xation) simulating post-mortem changes....Continue reading →

Address of editorial Corresponce
✎  Vorachai Sirikulchayanonta, MD, Editor-in-Chief: Asian Archives of Pathology, Faculty of Science, Rangsit University, Pathumthani 12000, Thailand.
✉  Email address: asianarchpath@gmail.com, vorachai7@gmail.com