Keyword : colorectal cancer

Prevalence of Microsatellite instability (MSI) determined by immunohistochemical staining of MSH6 and PMS2 in patients with colorectal adenocarcinoma

Microsatellite instability(MSI) is one of the genetic abnormalities that leads to colon cancer. The defect, known as mismatch repair genes(MMR) can be either sporadic or a germ line mutation. A immunohistochemical study is one of the methods to detect MMR defects. Lots of different treatment modalities and prognosis are needed to distinguish cancer...Continue reading →

Predictive Biomarker Testing in Colorectal Cancer: KRAS and BRAF Mutation Frequency and Testing Algorithm in Developing Countries

Predictive biomarker testing is mandatory before initiating targeted therapy in metastatic colorectal cancer (mCRC). Mutation frequencies and their association with clinicopathological features vary widely across populations. In low socio-economic countries, appropriate selection of cases is important for biomarker testing....Continue reading →

Address of editorial Corresponce
✎  Vorachai Sirikulchayanonta, MD, Editor-in-Chief: Asian Archives of Pathology, Faculty of Science, Rangsit University, Pathumthani 12000, Thailand.
✉  Email address: asianarchpath@gmail.com, vorachai7@gmail.com