Non-functioning adrenal cortical adenoma arising in adrenohepatic fusion, mimicking hepatocellular carcinoma – a case report

Publish : December 15, 2014
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Non-functioning adrenal cortical adenoma arising in
adrenohepatic fusion, mimicking hepatocellular
carcinoma – a case report

Napat Angkathunyakul, M.D.* Somkit Mingphruedhi, M.D.**, Penumpai Tanaphai M.D.***

*Department of Pathology, Faculty of medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

**Department of Surgery, Faculty of medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

***Department of Radiology, Faculty of medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

Correspondence:

Napat Angkathuyakul, M.D.

Department of Pathology, Faculty of medicine Ramathibodi Hospital, Mahidol University, 270 Rama Vi Road, Ratchatewi, Phayathai, Bangkok, 10400, Thailand 10400

Tel+662-201-1432, 662-201-1667

E-Mail: napat.ang@mahidol.ac.th

Received: 24 April 2014; Accepted: 28 September 2014.

ABSTRACT

Adrenal cortical adenoma arising in adrenohepatic fusion is an exceedingly rare occurrence. It can potentially be misinterpreted as hepatocellular carcinoma as they share radiologic and histologic similarities. We report an incidental subcapsular adrenal cortical adenoma arising in adrenohepatic fusion tissue in segment 7 of the liver in a 60 year-old female. The tumor contains all three components of adrenal cortical tissue (predominantly zona fasiculata-like area), with positive immunorcactivity for Melan-A, calretinin, a-inhibin and CD56; Hep Par-1, glypican-3 and chromogranin A are negative.

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Address of editorial Corresponce
✎  Vorachai Sirikulchayanonta, MD, Editor-in-Chief: Asian Archives of Pathology, Faculty of Science, Rangsit University, Pathumthani 12000, Thailand.
✉  Email address: asianarchpath@gmail.com, vorachai7@gmail.com