GLUT1 expression in non-Hodgkin lymphoma diffuse large B-cell lymphoma clinical and International Prognostic Index analysis
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Charoenlap C1, Julamanee J2, Mitarnun W1
1Department of Pathology, 2Department of Internal Medicine, Hematology Unit, Faculty of Medicine, Prince of Songkla Unisersity, Songkla, Thailand
High levels of glucose transporter 1 (GLUT1) expression are correlated with aggressiveness and poor outcomes in many malignancies. There were few studies of this correlation in non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and have heterogeneity in clinical outcomes.
Objective: The aims of this study to evaluate the expression of GLUT1 in DLBCL and correlate the association between their expression with International Prognostic Index (IPI) risk groups and overall survival.