Auther : 2

Pulmonary alveolar proteinosis coexisting with homozygous hemoglobin E

Pulmonary alveolar proteinosis (PAP) is an uncommon lung disorder of obscure and possibly diverse causes characterized by abnormal accumulation of lipoproteinaceous surfactant material in alveoli. The prevalence of acquired PAP has been estimated to be 0.37 per 100,000 populations. We present a case of PAP coexisting in homozygous hemoglobin (Hb) E....Continue reading →

Developing Pathology Services in Resource Poor Settings An Invitation to the International Academy of Pathology Meeting Bangkok 2014

The delivery of high quality laboratory medicine services in developing countries of low economic resources poses particular problems. International efforts to help develop pathology take many forms and include educa- tional and training initiatives by a number of organisations, although these are often disparate. In this article we will...Continue reading →

Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow

Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of primary marrow diseases. This study is designed to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals after taken out from the body (delayed fi xation) simulating post-mortem changes....Continue reading →

Acute and subchronic oral toxicity of xanthones extracted from the pericarp of Garcinia mangostana Linn.in rat

The purpose of this research was to study the acute and subchronic toxicity of crude mangosteen pericarp hydro extract, and determine the appropriate and safe amount of extract that may be consumed, through testing with Sprague Dawley rats of both sexes. The soft layer of the inner pericarp mangosteen fruits was immersed in water and boiled at 70 OC, and...Continue reading →

Molecular diagnosis of synovial sarcoma: A comparative study with histologic correlation in Ramathibodi Hospital

Synovial sarcoma (SS) is a relatively common sarcoma of soft tissue arising on extremities of young adult, which is often diagnosed by histology and immunohistochemistry. Synovial sarcoma can have various locations and may cause diagnostic dilemma in tumors arising on unusual locations. In this study, we evaluate the application of molecular test...Continue reading →

Disseminated Tuberculosis in a Mother with Diffuse Large B-cell Lymphoma resulting in Placental and Inferred Congenital Tuberculosis: An Autopsy Case Report

Tuberculosis of the placenta is a rare condition which mainly occurs in the immunosuppressed individuals especially in acquired immune deficiency syndrome (AIDS) and hematologic malignancy9. Tuberculosis can spread to the fetus via hematogenous or cervicovaginal route and result in congenital tuberculosis....Continue reading →

Primary central nervous system lymphoma presenting with panhypopituitarism and diabetes insipidus

Lymphoma involving the hypothalamus is very rare. We present a case of a 48-year-old man with primary central nervous system lymphoma (PCNSL) presenting with hypothalamic and pituitary stalk lesions with frontal masses, causing diabetes insipidus and panhypopituitarism. Brain MRI with gadolinium enhancement demonstrated vivid enhancing hypothalamic and...Continue reading →

Incomplete pentalogy of Cantrell: a case report

Pentalogy of Cantrell is a rare congenital syndrome characterized by defects involving the supra-umbilical abdominal wall, lower sternum, anterior diaphragm, pericardium, and the intra-cardiac anomalies. The ensuing congenital heart disease is a source of major morbidity. The full spectrum of the syndrome is rare while incomplete expression of the...Continue reading →

Neuroendocrine Tumor of the Gallbladder with Hepatic Metastases: A Case Report

A 68-year-old woman presented with hepatic metastasis. She had been performed cholecystectomy at a provincial hospital for symptomatic gallstones and was diagnosed as poorly differentiated adenocarcinoma of the gallbladder. The follow-up hepatic segmentectomy revealed a malignant small round tumor composed of nests of cells containing small nuclei...Continue reading →

GLUT1 expression in non-Hodgkin lymphoma diffuse large B-cell lymphoma clinical and International Prognostic Index analysis

High levels of glucose transporter 1 (GLUT1) expression are correlated with aggressiveness and poor outcomes in many malignancies. There were few studies of this correlation in non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and have heterogeneity in clinical outcomes....Continue reading →

Hepatitis B Virus infection is not a risk factor in liver fluke-associated cholangiocarcinoma – a comparative study of P53 mutation between groups with Opisthorchis viverrini and HBV infection

To investigation the role of HBV infection as a risk factor in liver fluke-associated cholangiocar-cinoma In Northeast (NE) Thailand, people are exposed to numerous risk factors for cholangiocarcinoma, such as: infestation with the liver fluke, Opisthorchis vivenini, hepatitis B virus (HBV) and hepatitis c virus (HCV) infection, and nitrosamine...Continue reading →

Similar expression of cytokeratin (CK7+/CK20+), Her-2, P53 and CA 125 in intrahepatic and extrahepatic cholangiocarcinoma: an immunohistochemical study

To evaluate cytokeratin CK7+/CK20+ and common oncogene, tumor suppressor gene and tumor marker in intrahepatic and extrahepatic cholangiocarcinoma. In 2009, the American Joint Committee on Cancer regrouped extrahepatic cholangiocarcinoma (EH-CCA) by placing hilar...Continue reading →

Soft tissue vascular malformations differentiating flow types by MR imaging and comparison with histopathology

To evaluate the MR imaging features of pathologically diagnosed high and low flow vascular malformations....Continue reading →

Molecular diagnosis of synovial sarcoma: A comparative study with histologic correlation in Ramathibodi Hospital

Synovial sarcoma (SS) is a relatively common sarcoma of soft tissue arising in extremities of young adult, which is often diagnosed by histology and immunohistochemistry (IHC). Synovial sarcoma can be found in various locations and may cause diagnostic dilemma in tumors arising in unusual locations. In this study, we evaluated the application of...Continue reading →

A case of intestinal perforation due to age-related EBV-associated B-cell lymphoproliferative disorder

Age-related Epstein-Barr virus (EBV)-associated lymphoproliferative disorder (LPD) is a recently novel EBV-positive clonal B-cell proliferation, occurring in patients >50 years old without any known immunodeficiency or prior lymphoma. The disease is believed to be related to immunological deterioration derived from the aging process and has aggressive...Continue reading →

Comparison of Histopathology and Mammography for breast lesions. Retrospective study of 250 cases in Srinagarind Hospital, Khon Kaen, Thailand.

To assess the pathologic outcome of BI-RADS mammographic classification and the success of stereotactic biopsy for such lesions. Materials and...Continue reading →

Increases of pro-inflammatory cytokine expression in hippocampus following chronic paracetamol treatment in rats

Paracetamol is one of the most popular drugs used for treatment of pain and headaches. Recent evidences have indicated that long term treatment with this drug can induce the neurotoxic effect in the brain including in the hippocampal neurons, however the mechanism underlying its neurotoxic effect is still unclear. The present study aimed...Continue reading →

Predictive Relevance of Tumor-infiltrating Lymphocytes in Breast Cancer

To determine the prognostic significance of the immunophenotype, density and distribution of tumor-infiltrating lymphocytes (TILs) in breast cancer samples....Continue reading →

Axillary lymph node ratio is an independent prognostic factor in Thai breast cancer patients

The number of metastatic lymph nodes to the total number of dissected axillary lymph nodes (lymph node ratio: LNR) is described as an independent prognostic factor in breast cancer patients, beside the traditional account of the number of axillary lymph node metastasis (pN stage). We investigated the correlation between LNR and prognosis among Thai...Continue reading →

Contribution of MYC FISH in Pathological Diagnosis of Burkitt Lymphoma

Burkitt lymphoma (BL) is an aggressive B-cell non-Hodgkin lymphoma typically with MYC rearrangement. Distinction between BL and diffuse large B cell lymphoma (DLBCL) is not infrequently encountered in routine practice. In this communication, we report our experience with the MYC break-apart probe FISH in the diagnosis of BL in 19 cases of...Continue reading →

Hepatic injury in patients with colorectal liver metastasis in Thailand

The treatment of colorectal liver metastasis is surgical resection. The chemotherapy can convert unresectable lesions to resectable lesions. However chemotherapy also causes liver injuries in remaining liver parenchyma, such as steatosis, steatohepatitis and sinusoidal dilation. These lesions cannot be distinguished from other causes,...Continue reading →

Clinicopathological Features of Primary Thyroid Lymphomas in Thailand

Primary non-Hodgkin lymphoma (NHL) of the thyroid is a rare tumor. Some studies show association between thyroid lymphomas and concomitant thyroid diseases, mainly lymphocytic thyroiditis. However, this tumor has not been studied in Thailand. .Therefore, herein, we reviewed clinicopathological features of primary thyroid lymphoma including associated thyroid lesions....Continue reading →

Clinicopathological Correlation of Glomerular Mesangial C4d Staining and renal outcome in IgA Nephropathy: A retrospective Cohort Study in Ramathibodi Hospital

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, particularly in Asia. Clinical manifestations vary from asymptomatic to end stage renal disease (ESRD). Currently, several studies have introduced new markers to predict prognosis including C4d which is correlated with poor clinical course....Continue reading →

Discrepancies between clinical and autopsy diagnosis in traumatic death cases in Siriraj Hospital

Hospital autopsy has been questioned regarding its utility, effectiveness, and validity. However, some discrepancies between clinical and autopsy diagnosis has been shown in previous study.While forensic autopsy, which is mostly done in traumatic death, has not been evaluated for its usefulness, the authors would like to determine...Continue reading →

Pulmonary neuroendocrine hyperplasia in hemoglobin Bart-induced hydrops fetalis. A model for chronic intrauterine hypoxia

The pulmonary neuroendocrine system consists of pulmonary neuroendocrine cells (PNECs) and neuroendocrine bodies (NEBs) distributed throughout the respiratory epithelium which regulate lung growth and maturation in the antenatal period. Abnormalities in this system have been linked to many hypoxia-associated pediatric pulmonary disorders....Continue reading →

Automated counting of Ki-67 labeling index compares with eyeballing estimation to predict behavior of pituitary adenoma.

Pituitary adenoma has been classified as benign according to slow-growing tumor. However, some atypical pituitary adenoma may have clinical aggressiveness such as parasellar invasion and high recurrence rate.Many studies have failed to demonstrate a correlation between Ki-67 labeling index and behavior of this tumor....Continue reading →

Placental villous hypermaturation in idiopathic spontaneous preterm births in Srinagarind Hospital

To determine the association between preterm births (PTBs) and placental villous hypermaturation (PVH), a pathological fi nding which suggests placental insuffi ciency....Continue reading →

Anaplastic lymphoma kinase (ALK) translocation in paediatric malignant peritoneal mesothelioma: a case report of novel ALK-related tumour spectrum

To report a case of paediatric malignant peritoneal mesothelioma (MPM) with evidence of anaplastic lymphoma kinase (ALK) translocation....Continue reading →

The Akt/mTOR pathway is activated in verrucous carcinoma of the oral cavity

The Akt/mTOR pathway is activated in many malignancies including oral squamous cell carcinoma (OSCC). Oral verrucous carcinoma (OVC) is a low grade variant of OSCC. However, the role of the Akt/mTOR pathway in OVC remains unknown. ...Continue reading →

Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow

Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of pathologic processes. Objective: This study is to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals...Continue reading →

Gap Analysis Study before Implementation of Thailand’s National Guidelines for Point of Care Testing at Chiang Rai Province

The Bureau of Laboratory Quality Standards has published Thailand’s National Guidelines for Point-of-Care Testing (POCT) since August 2015. Still yet, the implementation of the guidelines is a great challenge....Continue reading →

Thrombotic microangiopathy with Atypical Posterior Reversible Encephalopathy Syndrome (PRES) after kidney transplantation. A case report.

Neurological manifestation of thrombotic microangiopathy (TMA) after renal transplantation is rare and difficult to be distinguished from other conditions. A 51-year-old female with ESRD of unknown etiology received deceased donor kidney transplantation from a 57-year-old donor....Continue reading →

Address of editorial Corresponce
✎  Vorachai Sirikulchayanonta, MD, Editor-in-Chief: Asian Archives of Pathology, Faculty of Science, Rangsit University, Pathumthani 12000, Thailand.
✉  Email address: asianarchpath@gmail.com, vorachai7@gmail.com