Increases of pro-inflammatory cytokine expression in hippocampus following chronic paracetamol treatment in rats

Paracetamol is one of the most popular drugs used for treatment of pain and headaches. Recent evidences have indicated that long term treatment with this drug can induce the neurotoxic effect in the brain including in the hippocampal neurons, however the mechanism underlying its neurotoxic effect is still unclear. The present study aimed...

Author : Chattraporn Chantong1, Waranurin Yisarakun1, Thananya Thongtan2, Supang Maneesri-le Grand1*
Keyword : hippocampus, il-1a, paracetamol, pro-inflammatory cytokines, tnf-a