[OA-22] The adjusted protocol in cryosection of axillary sentinel lymph node reduces the overall diagnostic discordance

The cryosection of axillary sentinel lymph node is usefol for intraoperative decision in breast cancer patients. However, the consequence from cryosection-permanent section discordance, mainly from sampling error, still occurs. The aim of this study was to evaluate discordant rate, as well as its cause, of the adjusted protocol for cryosection in axillary sentinel lymph node compared to the traditional protocol. ...

Author : Phongamorn Rattanasiriphibun, Wiyada Dankai, Surapan Khunamornpong, Suree Lekawanvijit
Keyword : axillary sentinel lymph node, cryosection, discordance, sampling error
Category : Brief communications

Comparison between unbuffered and buffered formalin fixatives for estrogen receptor and Ki-67 immunostains in breast cancer specimens: a pilot study

Pre-analytic steps are important for the immunohistochemical study as in the case of breast cancers. The initial process is the fixation in which the 10% neutral buffered formalin (NBF) is recommended. 10% formalin is less expensive and easier to prepare but its effect on the immunostaining is controversial....

Author : Chetsada Chunkaruhart, Nopporn Tipparawong, Kroonpong Iampenkhae
Keyword : 10% formalin, 10% neutral buffered formalin, ER, Ki-67, breast cancers
Category : Original Articles