[RA-11] Next-generation sequencing in pathology: enabling personalised medicine
Personalised medicine promises to minimize health care costs by shifting from a standard medical model of treating pathologies to a tailored predictive and preventative one. Next-generation sequencing (NGS) has the potential to speed up the early detection of diseases as well as the identification of pharmacogenetic markers that can be used to personalize treatments....
[RA-04] Current concept of membranoproliferative glomerolonephritis
Membranoproliferative glomerolonephritis (MPGN) is used to be classified as MPGN type I, II and III. The older classification only gave a diagnosis but did not include the aetiology and pathophysiology of the disease. The new classification gives the clinician more detail and leads to proper treatment. The old and new classification of MPGN include aetiology,...
[OA-27] A study of tumour-infiltrating lymphocyte in distal cholangiocarcinoma
Cholangiocarcinoma (CCA) is one of major cancer in Northeast Thailand. Studies reveal tumours can induce immune response due to their altered protein products recognised as foreign bodies by the immune system. Tumour-infiltrating lymphocytes (TILs) can be assessed to represent the mentioned immune response. Recently, TILs are a potential predictive factor of prognosis in many solid tumours; still, data researched in CCA are limited. This study aimed to assess TILs in distal cholangiocarcinoma according to The International TILs Working Group (ITWG) guideline and to correlate it with...
The essentials of vascular pathology
Vascular pathology is defined as the abnormalities of the arterial and venous blood vessels and the lymphatic vessels. Endothelial cell injury usually leads to the development of either arterial or venous change.The lymphatic diseases mostly result from inflammation, infection, and neoplasm....