Acute and subchronic oral toxicity of xanthones extracted from the pericarp of Garcinia mangostana Linn.in rat

The purpose of this research was to study the acute and subchronic toxicity of crude mangosteen pericarp hydro extract, and determine the appropriate and safe amount of extract that may be consumed, through testing with Sprague Dawley rats of both sexes. The soft layer of the inner pericarp mangosteen fruits was immersed in water and boiled at 70 OC, and...

Author : Kanokporn Chayaburakul1, Patamaporn Sukplang2, Thanaporn Pinpart3 and Kanjana Kengkoom4
Keyword : acute and subchronic toxicity, clinical chemistry, histological examination, kidney, mangosteen pericarp hydro extract
Category : Original Articles