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Type VII collagen is a main component of anchoring fibrils, providing stability to the dermal-epidermal adhesion. Its reduction or absence has been associated with an increased risk of squamous cell carcinoma (SCC). This study aimed to evaluate type VII collagen expression in oral SCC compared to normal oral mucosa and its relationship with cancer stages....

Known for their poor outcomes, triple-negative breast cancers (TNBCs) have been investigated for immune checkpoint inhibitors that target Programmed death ligand 1 (PD-L1). In the recent decade, tumour-infiltrating lymphocytes (TILs) have also become potential biomarkers. The aim of the study was to determine the reproducibility of PD-L1 scoring system and TILs interpretation in the local setting through intra- and interobserver agreement....

Primary lymphoma of bone (PLB) is an extranodal lymphoma that arises in osseous sites with no evidence of disease elsewhere for at least 6 months. They account for 3% of malignant bone tumours and 1% of all lymphomas. Secondary involvement of bone by lymphoma. This study analysed the clinicopathological features and outcomes of a series of PLB....

The incidence of placenta accreta spectrum (PAS) has inclined with the increasing of cesarean deliveries (CD). It is divided into 3 groups based on the invasion of the chorionic villi into the myometrium (accreta, increta and percreta). The aim was to determine the correlation between clinicopathology and the depth of chorionic villi invasion of PAS....

Sinonasal teratocarcinosarcoma is rare malignant tumour arising in sinonasal region. On Histopathological examination, this tumour is characterised by the combination of benign and malignant components of epithelial, mesenchymal and teratoid elements. Sinonasal teratocarcinosarcoma is more common in male, tends to locally damage with high recurrence rate....

Malignant triton tumour (MTT) is a rare neoplasm, approximately 170 cases have been reported. Diagnosis of this tumour requires attention to the clinical, histopathological, immunohistochemical and prognosis features of this neoplasm....

Primary malignant melanoma of the lung (PMML) is rare, with limited published reports. This case report discussed the diagnosis and management of a PMML occurring in a young patient and reviewed existing literature....

Paediatric gastric adenocarcinoma (GAC) is an extremely rare with limited relevant data. Until now, the clinical presentation and outcome have not yet been thoroughly understood....

Histiocyte-rich pseudotumour (HPRT) developing post-chemoradiation therapy is a rare benign reaction. Although benign, it can clinically and radiologically mimic residual tumours or recurrent/relapsed disease, causing challenges in management....

Tumours primarily arising from the appendix are not common, comprising only 0.9% - 1.4% of all documented appendectomies. Among all appendiceal neoplasms, majority of cases are of well-differentiated neuroendocrine tumours. Appendiceal leiomyosarcomas are rare with only a few cases reported. Thus, diagnosis and management of this tumour is based on the behaviour of leiomyosarcoma of the colon....