Update in Thymoma for Surgical Pathologists
Thymoma is the most common mediastinal tumor in adulthood. By definition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral heterogeneity...
Is immunohistochemistry mandatory in staging bone marrow trephine biopsy of patients with diffuse large B-cell lymphoma (DLBCL)
Diffuse large B-cell lymphoma (DLBCL) can be found involving bone marrow in approximately 11-27% of cases 1. Patterns of involvement are variable; these include diffuse pattern (lymphomatous cells diffusely infiltrating the marrow), interstitial pattern (i.e. small amount of lymphomatous cells scattered among hematopoietic cells), nodular pattern (lymphomatous cells forming aggregates in intertrabecular or paratrabecular area of the marrow).. ...
Update in Thymoma for Surgical Pathologists
Thymoma is the most common mediastinal tumor in adulthood. By defi nition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral...
Diagnostic Pitfalls of Prostatic Adenocarcinoma in Biopsy Specimens
Prostatic adenocarcioma is a very common male cancer worldwide. Biopsy remains the most reliable means in making definite diagnosis. In the prostate-specific antigen (PSA) screening era, the rate of prostate biopsies rapidly increases, resulting in early detection of very small tumors. In the same time, general pathologists are forced to face...