[P-28] Spectrum of gastric subepithelial lesions encountered on EUS-FNA: a single centre experience

Poojan Agarwal1, Pooja Bakshi1, Kusum Verma1, Vikas Singla2 and Anil Arora2

  1. Department of Cytopathology, Sir Ganga Ram Hospital, New Delhi, India
  2. Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India

 

Background and Objectives: Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a minimally invasive and reliable non‑surgical technique for diagnosis of gastrointestinal lesions. The present study aimed at evaluating the spectrum of lesions encountered in the gastric subepithelium on EUS-FNA at a tertiary care centre.

Materials and Methods: Archival data of all patients undergoing EUS-FNA for gastric submucosal lesions over a period of five years was retrieved. Patient demographics, clinical presentation and EUS findings were recorded along with the FNA results.

Results: A total of 78 EUS-FNA samples were analysed. Material was adequate in 68 cases (87.17%) and inadequate in 10 cases (12.22%) patients due to scant cellularity. Of the adequate samples, 33 (42.3%) were reported as neoplastic while 27 (34.61%) were non-neoplastic and 8 (10.25%) were reported as suspicious of a neoplasm. In the neoplastic category, the predominant diagnosis was of spindle cell neoplasm comprising gastrointestinal stromal tumour (13 cases), benign neural tumour (3 cases), leiomyoma (2 cases) and spindle cell tumours (3 cases). The latter could not be categorised further due to lack of IHC material. The next common diagnosis was adenocarcinoma (6 cases) followed by neuroendocrine tumour (2 cases) and poorly differentiated carcinoma (1 case). The non-neoplastic lesions included non-specific pathology (15 cases), inflammatory lesions (8 cases) and one case each of tuberculosis, pancreatic rest and Brunner gland hamartoma. Cell blocks for ancillary testing were available in 51 cases (65.38%) and follow-up was available in 42 cases (53.84%).

Conclusion: EUS-FNA is a good modality for diagnosis of gastric submucosal lesions with a high diagnostic yield.