[OA-34] The use of artificial intelligence in diagnosis of papillary thyroid carcinoma
Thyroid cancer is considered the most common endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most predominant form, accounting for 85% of all diagnoses. Due to the diagnostic dilemma that can commonly occur in these neoplasms, artificial intelligence (AI) technology has been attempted to assist the diagnosis of these cancers. ...
[OA-18] Histone 3 and histone 4 acetylation pattern in well-differentiated thyroid neoplasms and nodolar goitre
Several epigenetic mechanisms of oncogenesis such as histone acetylation and DNA methylation are now known to play a key role in developing cancers. So far, these molecolar events have rarely been evaluated in thyroid neoplasms. The aim of this study was to estimate the histone acetylation level in benign and malignant thyroid lesions and compare it to the normal counterpart....
Cytotoxic effect of lutein extracts from marigold flower in Lens epithelial cell line
Lutein is a carotenoid found in the lens of the human eyes. Its functions are to protect the eyes by filtering a hazard blue light and to prevent vision loss due to cataract formation. Lutein could not be synthesised in the body and must be taken from the diet, however, lutein is isolated from a marigold flower....
Comparison of α-smooth muscle actin expression between squamous cell carcinoma and pseudoepitheliomatous hyperplasia
To evaluate the usefulness of α-smooth muscle actin (α-SMA) expression of reactive myofibroblastic cells within desmoplastic reaction tissue for distinction between invasive squamous cell carcinoma (SCC) and pseudoepitheliomatous hyperplasia (PEH)....
Primary central nervous system lymphoma presenting with panhypopituitarism and diabetes insipidus
Lymphoma involving the hypothalamus is very rare. We present a case of a 48-year-old man with primary central nervous system lymphoma (PCNSL) presenting with hypothalamic and pituitary stalk lesions with frontal masses, causing diabetes insipidus and panhypopituitarism. Brain MRI with gadolinium enhancement demonstrated vivid enhancing hypothalamic and...
The Many Faces (and Origins) of Adenocarcinoma in the Liver: Pattern Approach to Diagnosis on Small Tissue Samples
Focal liver lesions can be solitary or multiple, solid or cystic, congenital or acquired, and range from cysts, hamartomas, hyperplastic nodules and inflammatory entities to tumors and tumor-like lesions. The background liver may be normal or diseased. An algorithmic approach based on pattern recognition and cell profiling is outlined for the ...