A Comparison Study of Molecular Classification of Primary Invasive Breast Carcinoma and Corresponding Metastatic Carcinoma in Axillary Lymph Nodes by Immunohistochemistry

Breast cancer is a heterogeneous disease. There is a high degree of diversity between and within tumours as well as among cancer-bearing individuals, and all of these factors together determine the risk of disease progression and therapeutic resistance....

Author : Tanyasorn Sutthipongsupa, Kittisak Wongchansom, Panjawit Wuttipanich, Mongkon Charoenpitakchai
Keyword : Breast cancer, heterogeneity, molecular phenotypes, paired node, ER, PR, HER2, Ki67, CK5/6, EGFR, p53
Category : Original Articles

Predictive Biomarker Testing in Colorectal Cancer: KRAS and BRAF Mutation Frequency and Testing Algorithm in Developing Countries

Predictive biomarker testing is mandatory before initiating targeted therapy in metastatic colorectal cancer (mCRC). Mutation frequencies and their association with clinicopathological features vary widely across populations. In low socio-economic countries, appropriate selection of cases is important for biomarker testing....

Author : Niraj Kumari, Narendra Krishnani, Ashok Kumar, Balraj Mittal
Keyword : metastatic colorectal cancer, kras, braf, predictive biomarker, anti-egfr
Category : Original Articles