Pathology

Personalised medicine promises to minimize health care costs by shifting from a standard medical model of treating pathologies to a tailored predictive and preventative one. Next-generation sequencing (NGS) has the potential to speed up the early detection of diseases as well as the identification of pharmacogenetic markers that can be used to personalize treatments....

Diagnosis of lymphomas is complex and requires resource higher than common cancers. In the difficolt cases, the general pathologists coold request external consoltation (EC) for the interpretive judgment from the haematopathologists. The aim of this review is to reveal recent international experiences of external consoltation in lymphoid neoplasms (LN). Regarding the EC of LN, the major diagnostic revision ranges from 16% to 55% with non-...

Membranoproliferative glomerolonephritis (MPGN) is used to be classified as MPGN type I, II and III. The older classification only gave a diagnosis but did not include the aetiology and pathophysiology of the disease. The new classification gives the clinician more detail and leads to proper treatment. The old and new classification of MPGN include aetiology,...

Fine needle aspiration (FNA) cytology is efficient in guiding salivary gland lesions management. Lack of standardised reporting complicates communication between pathologists and clinicians. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been proposed to improve reporting uniformity. This study aimed to reclassify salivary gland FNA and evaluate risk of malignancy (ROM) in each diagnostic category. All salivary gland FNA cytology in Srinagarind Hospital from January 2013 to December 2019...

Cholangiocarcinoma (CCA) is one of major cancer in Northeast Thailand. Studies reveal tumours can induce immune response due to their altered protein products recognised as foreign bodies by the immune system. Tumour-infiltrating lymphocytes (TILs) can be assessed to represent the mentioned immune response. Recently, TILs are a potential predictive factor of prognosis in many solid tumours; still, data researched in CCA are limited. This study aimed to assess TILs in distal cholangiocarcinoma according to The International TILs Working Group (ITWG) guideline and to correlate it with...

Intracranial germ cell tumours (ICGCTs) are rare; current treatment depends on tumour secreting status. ICGCTs with beta-hCG > 50 U/L or/and AFP > 10 ng/dL do not need histopathology before treatment initiation. Correlation of clinical, pathological diagnosis and reliability of tumour marker cut-off values are unknown. The aim of this study was to describe clinico-radio-pathological characters of ICGCTs, ...

Vascular pathology is defined as the abnormalities of the arterial and venous blood vessels and the lymphatic vessels. Endothelial cell injury usually leads to the development of either arterial or venous change.The lymphatic diseases mostly result from inflammation, infection, and neoplasm....

Pathology courses are taught to undergraduate medical students to provide them with basic foundation for clinical sciences. However, there is hardly any form of assessment of how relevant and helpful these pathology courses are to the students in the clinical years and even beyond. ...

In 2010 Department of Pathology Siriraj Hospital had introduced a standardization program for reporting colorectal carcinoma. Then the completeness and accuracy of pathology reports were assessed. Slides were reviewed for accuracy of pT stage and rectal circumferential margin status. After standardization program the percentage of pT4 lesion...

Fine needle aspiration (FNA) cytology of suspected salivary gland lesions has an established role in preoperative diagnosis and management of patients. However diverse morphological patterns and overlapping features make it a challenging job, to give a precise diagnosis, at times. The aim of the present study is to investigate the accuracy...