Determination of Asbestos Bodies in Autopsy Lung Fluid
The finding of asbestos bodies in lung fluid aspirates represents definite evidence of having prior exposure to asbestos, and having asbestos fibers entering the bronchial tree. After entering the lung, fibers undergo a coating process with ferritin protein to form asbestos bodies. The present study was carried out with the aim of determining...
Angioimmunoblastic T-Cell Lymphoma: an Epstein-Barr Virus-Associated, Bilineage Lymphoid Neoplasm
In this study, 50 cases of angioimmunoblastic T-cell lymphoma (AITL) were investigated for histological patterns, their association with Epstein-Barr virus (EBV) infection, B cell and T cell clonalities, and the clini- cal outcomes. Three histological patterns were identified: the classical pattern (34 cases), large-cell rich pat- tern (14 cases)...
Increases of pro-inflammatory cytokine expression in hippocampus following chronic paracetamol treatment in rats
Paracetamol is one of the most popular drugs used for treatment of pain and headaches. Recent evidences have indicated that long term treatment with this drug can induce the neurotoxic effect in the brain including in the hippocampal neurons, however the mechanism underlying its neurotoxic effect is still unclear. The present study aimed...
Comparison of Histopathology and Mammography for breast lesions. Retrospective study of 250 cases in Srinagarind Hospital, Khon Kaen, Thailand.
To assess the pathologic outcome of BI-RADS mammographic classification and the success of stereotactic biopsy for such lesions. Materials and...
Impact of CpG site specific methylation on silencing protein expression of GSTP1 in breast cancer
From previous study with Methylation specific polymerase chain reaction (MSP), there were cases of DNA methylation showing positive protein expression. Some CpG sites of the primer were speculated to have no effect on protein expression....
Increased eosinophil levels in HIV-infected patients with high CD4/CD8 ratio Study from 564 patients in Ramathibodi Hospital.
Blood from 564 patients infected with human immunodeficiency virus (HIV) were studied for laboratory analysis. The hematological changes including white blood cell count (WBC), percentage and absolute number of lymphocyte and eosinophil were determined by using the Technicon H*3 RTX hematological analyzer. Analysis of blood cell parameters...
Advantage of frozen section in management of thyroid nodule with preoperative fine needle aspiration in Siriraj Hospital, Bangkok, Thailand
We aimed to evaluate the role of frozen section (FS) and preoperative fine-needle aspiration cytology (FNA) in thyroid nodular lesions. ...
Diagnostic accuracy of fine needle aspiration cytology of salivary glands
Fine needle aspiration (FNA) cytology of suspected salivary gland lesions has an established role in preoperative diagnosis and management of patients. However diverse morphological patterns and overlapping features make it a challenging job, to give a precise diagnosis, at times. The aim of the present study is to investigate the accuracy...
The role of Immunohistochemistry in diagnosis of renal cell carcinoma subtypes.
To determine the validity of immunohistochemistry in classifying Renal cell carcinoma (RCC) subtypes. Methods: Eighty-three cases of RCC were retrieved. Immunohistochemical staining of Vimentin, CD10, CK7, P504s, Parvalbumin, TFE3, and CD117 were done by using tissue microarray blocks. RCC subtypes were placed and compared with the previous diagnosis....
Loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis and evaluation in paraffin-embedded lymph nodes
Tuberculosis is a treatable disease, but remains a major cause of mortality. Culture for Mycobacterium is needed to make a definitive diagnosis; thus, loop-mediated isothermal amplification (LAMP) was attempted for its detection in formalin-fixed, paraffin-embedded (FFPE) samples. Materials and method: Archival FFPE blocks were used from 64 patients...